2.1.1 Use Case Overview Initial State / Pre-condition: Kurt, a clinical project team leader (research physician) at pharma 'A' has restricted permissions to extract information from medical records (c.f. Table 1). These permissions allow Kurt to perform a cross-enterprise request to view a summary extract from patient records at hospital 'B' and hospital ‘C’. Kurt’s name or his unique identification specific to organization 'A' is not known to hospital ‘B’ or ‘C’. The purpose of use is ‘Patient availability’, i.e. investigation of subject availability to meet a specified set of inclusion/exclusion criteria.. Hospital ‘B’ and ‘C’ have collaboration agreement with pharma ‘A’ regulating the information access. E.g. only patients with no specified constraints for research involvement will be included in the returned result. Scenario: Kurt is responsible to design a COPD study and want to understand what patient profiles are available. He therefore plan to perform a cross-enterprise viewing of medical records for COPD patients. Typical information to ask for could be; What number of COPD patients are available in ‘B’ and ‘C* groped by severity (mild, moderate and severe). For each identified patients include: age, sex, smoking status and pack years, lung function (FEV1 and FEV1/FVC), prior CT, CRP level in mg/l, co-morbidity (additional diagnosis), polymorphism in ADME genes. RESULT: Kurt is able to access the medical record including sensitive data but without any identities.. Kurt at BioPharma Pandora gives him signed statement to say he's in the research group, Smooth Muscle BigCity Hospital has info about COPD patients BigCity has delegated it to John Smith